Developmental Immunology

The Department of Developmental Immunology consists of two independent research groups. The immune system develops from hematopoietic precursor cells in the bone marrow. These precursors go through rounds of cell division and differentiation to give rise to the various different lymphoid and non-lymphoid lineages that go to make up the innate and adaptive immune systems.

The immunologists are investigating the origin and evolution of lymphoid organs and the adaptive immune system, the intestinal immune system, and adaptive and innate immunity with a focus on various aspects of immune tolerance. The immune system which initiates its development far before birth with in the fetus and because of which the development continues even after reaching the adulthood. The capacity to react to antigens and foreign invaders is thus dependent on: Age of the person, Type of antigen, maternal factors, Area of body.