Hadaf Dhafir Al Yaseen

Hadaf Dhafir Al Yaseen

University of Baghdad, Iraq



Biography

Hepatitis C virus (HCV) is a serious infectious disease that can cause lifelong infection. Infection with chronic hepatitis C virus (HCV) can lead to autoimmune hepatitis (AIH) in a minority of patients. Viral infection induces, both (in vivo and in vitro) tumor necrosis factor (TNF-alpha) production in hepatocytes, and these findings suggest that TNF-alpha may have an important role in human liver diseases induced by viruses, together with the prolactin hormone, which is an endocrinal hormone that acts like a cytokine involved in immune response. Our study showed that chronic hepatitis C virus infection associated with a statistical significant increase in the antismooth muscle antibody, while no statistical significant increase in antinuclear antibody were shown in this study.  The study elucidated a statistically non-significant increase in mean value of prolactin hormone in chronic hepatitis C patients but a significant increase in tumor necrosis factor-alpha. No significant correlations were found between prolactin hormone and tumor necrosis factor-alpha. The study concluded that chronic hepatitis C associated with an immunological abnormality mainly represented with antismooth muscle antibody. Tumor necrosis factor-alpha increased in chronic hepatitis C virus infection with no significant correlations with prolactin hormone

Abstract

Prof. Dr. Hadaf El-Yassin was faculty in University of Baghdad in the Department of Biochemistry, College of Medicine at University of Baghdad. She finished her Post Doctorate in Clinical Biochemistry at Al-Nahrain University. She is currently the head of the Department of Clinical Biochemistry, University of Baghdad, Iraq. She actively participated in 43 local conferences in Iraq and 26 abroad, making a total of 69 conferences attendance and paper presentation. She also published 85 articles